Spina bifida

Case contributed by Kathryn Phillips
Diagnosis certain

Presentation

Weak hind limbs and wound on top of tail head. Abnormally short tail since birth. Moderate generalized ataxia and paresis, full bladder, dribbling urine. Fever and omphalitis. Reduced sensation of anus and perineum. Left sided heald tilt.

Patient Data

Age: 4 d
Gender: Male
Category: Sheep
Organism: Jacob sheep breed

Lumbar spine

mri
  • Cutaneous defect at the level of the sacrococcygeal junction with underlying midline defect in the dorsal lamina of the sacral vertebrae

  • Large fluid filled sac herniating through this defect that communicates with the subarachnoid space

  • Spinal cord extends caudally and passes through the previously described laminar defect, individual nerve roots of the cauda equine are not visualized

  • Syringohydromyelia in the spinal cord just cranial to the defect

  • Markedly distended urinary bladder

Spina bifida at the sacrococcygeal junction with meningomyelocele.

 

Brain

mri
  • Marked caudal transtentorial herniation with bilaterally symmetric caudal extension of the occipital lobes and lateral ventricles

  • Moderate to marked herniation of the cerebellum through the foramen magnum with secondary ventral deviation of the brainstem at this level

  • Thinned and flattened occipital bone with a poorly defined osseous tentorium

Chiari malformation with transtentorial and foramen magnum herniation.

Necropsy

Photograph

The myelomeningocele was open and visible as a wound on the dorsal surface of the tail area. On dissection, the defect was elongated and extended to the spinal canal. The cauda equina was absent and the spinal cord appeared tethered. The spinal processes of the caudal vertebrae and sacral vertebrae 3 and 4 were absent.

The brain was deformed and caudally elongated secondary to the herniation through the foramen magnum. The tentorium cerebelli was absent, causing the severe subtentorial herniaton. Chiari type II malformation has been associated with spina bifida.

Case Discussion

The clinical signs of urine dribbling and sensation to anus and perineum are related to a cauda equina lesion, and the ataxia and head tilt refer to the brainstem and cerebellum.

Spina bifida is caused by failure of the neural tube to close. It may be an inherited disorder in sheep, and survival time is less than 25% past 5 days in one study.

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.