Panosteitis

Case contributed by Allison L Zwingenberger
Diagnosis certain

Presentation

Presents with mild forelimb lameness.

Patient Data

Age: 9 m
Gender: Male
Category: Domestic dog
Organism: Labrador retriever

Axial skeleton

x-ray

On a lateral radiograph of the right thoracic limb, there is increased mineral opacity in the medulla of the humerus and the radius. The humeral lesion is focal, and is located several centimeters proximal to the elbow. The radial lesion is more diffuse with a less well-defined zone of transition. The left thoracic limb has similar lesions but less extensive.

On the radiograph of the pelvis, both femurs have diffuse patchy increased opacity in the medulla.

Panosteitis.

Case Discussion

Panosteitis is a disease of growing dogs in which activity of osteoblasts and fibroblasts in the medulla, endosteum, and periosteum is increased. Areas of fibrovascular tissue are produced in the bone marrow which is replaced by woven bone in a continuing cycle. The lesions often originate near a nutrient foramen. German Shepherd dogs and other large breeds are predisposed. The disorder can affect multiple long bones at different times, resulting in shifting lameness. The most severe radiographic signs may not correlate with the lame limb. It is rare to see panosteitis in dogs over two years of age. The disorder resolves with symptomatic treatment.

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