Presentation
Presents with a 3-month history of progressive right thoracic limb lameness. In the past 2-3 weeks, the patient has also developed pelvic limb lameness.
Patient Data
There are round lytic lesions affecting multiple bones within the thoracic and pelvic limbs. Some of these lesions are causing cortical destruction. There is also lysis involving the distal aspect of the right and left humerus. There is severe periarticular remodeling of the right elbow.
Polyostotic aggressive bone lesions may be multiple myeloma or metastatic disease.
Case Discussion
Plasma cells were found on cytology of fine needle aspirates, indicating a multiple myeloma.
Radiologists often refer to bony lesions as being monostotic (affecting only one bone) or polystotic (affecting multiple bones). Deciding whether a lesion is mono- or polyostotic will help you to refine your differential diagnosis list. Primary bone tumors, for example, are almost always monostotic. Metastatic bone neoplasia, bone infections, or soft tissue tumors invading bone may be polyostotic.
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