Multiple myeloma

Case contributed by Allison L Zwingenberger
Diagnosis certain

Presentation

Presented with a 6-week history of cervical pain and progressive pelvic limb paresis. Tentative Diagnosis: C1-T2 lesion, possible C5-cranial.

Patient Data

Age: 10 years
Gender: Castrated male
Category: Domestic dog
Organism: Vizsla superbreed

Vertebral column

x-ray

The body of C7 is shortened and is radiolucent with thin cortices. The body of C3 is sclerotic compared to surrounding vertebrae.

Thoracic spine

mri

An MRI was performed, and contrast enhancing tissue was found in multiple cervical and thoracic vertebrae as well as in the spinal canal and venous sinuses. The C7 and T1-T3 vertebral bodies are contrast enhancing.

Spine

pathology

There is a compression fracture of the vertebral body with central lysis. A soft tissue component extends into the spinal canal.

Case Discussion

Differential diagnosis

Lucency of C7 and sclerosis of T3 are most consistent with an aggressive process such as neoplasia.

Necropsy examination found myeloma at these sites as well as invasion of the venous sinuses.

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