Presentation
Presented with weight loss and tachypnea for several months.
Patient Data
On radigoraphs of the thorax, there is dilation of the trachea with undulation in the thorax on the right lateral projection. There is a diffuse bronchial pattern with multiple regions of rounded radiolucency, especially in the cranioventral thorax. The lungs appear hyperinflated. The cardiovascular structures appear normal. There is poor detail in the peritoneal space and the animal is in thin body condition.
Impression:
Hyperinflation and bronchointerstitial pattern with pulmonary emphysema may be secondary to chronic lower airway disease with inflammation. The tracheal dilation is likely secondary to the increased respiratory effort and/or tracheomalacial.
The lungs had severe emphysematous changes, seen as expanded bullae at the edges in the photograph. There was consolidation and fibrous change.
Case Discussion
On necropsy, there was severe extensive fibrosis with bulla formation. Infiltration with Langerhans cell histiocytes wascausing pulmonary disease. The kidneys were also affected. The final diagnosis was feline pulmonary Langerhans cell histiocytosis (pLCH) with multiorgan involvement, a new and rare disease that may be inflammatory or neoplastic.
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