Chronic lower airway disease

Case contributed by Allison L Zwingenberger
Diagnosis certain

Presentation

Presents with chronic, progressive cough of 1‑year duration.

Patient Data

Age: 9 years
Gender: Spayed female
Category: Domestic cat
Organism: Siamese cat

Thorax

x-ray

There are mild diffuse bronchointerstitial infiltrates. There is focal mineralization caudal and slightly right-sided to the hilus within the lungs. There is also increased soft tissue opacity of the right cranial and right middle lung lobes with mild volume loss and rightward mediastinal shift. A lobar sign is visualized at the junction of the right middle and right caudal lung lobes on the left lateral projection.

Thorax

ct

There is complete collapse of the right cranial and right middle lung lobes, which are diffusely contrast enhancing and have multifocal heterogenous mineralization. There is an accumulation of mineral-dense material within the accessory bronchus, with near complete occlusion of the lumen. Wispy soft tissue material is also present in the right main stem bronchus, at the origin of the right cranial bronchus. Diffusely, there is marked airway thickening and patchy interstitial infiltrates.

Case Discussion

Chronic lower airway disease causing mucus plugging and atelectasis of the right cranial and middle lung lobes. Broncholiths.

On bronchoscopy, the right mainstem bronchus was largely occluded by a large, inspissated mucus plug. Multiple other bronchi on the right side were occluded with mucus and broncholiths, several of which were removed. Pathology showed mineralized material with eosinophilic infiltrate and necrotic tissue.

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