Adrenal carcinoma

Case contributed by Allison L Zwingenberger
Diagnosis certain

Presentation

Presents with panting, polydipsia, and muscle weakness.

Patient Data

Age: 12 years
Gender: Spayed female
Category: Domestic dog
Organism: Shih tzu dog

Abdomen

x-ray

The liver is mildly enlarged and rounded, extending beyond the costal arch. There is an oval, peripherally mineralized mass superimposed on the right kidney on the lateral projection, and located cranial and medial to the left kidney on the ventrodorsal projection. Both neutral and compression views of the urinary bladder are available. Small mineral opacities are visible in the bladder lumen. Radiopaque sutures are present in the ventral abdominal wall.

Adrenal glands

ct

There is a nodule in the cranial pole of the right adrenal gland. The left adrenal gland has a larger nodule in the caudal pole. There is heterogeneous bilateral central contrast enhancement of the adrenal glands. The phrenicoabdominal veins are not visible entering the caudal vena cava.

Case Discussion

Differential diagnoses for the adrenal nodules include carcinoma, pheochromocytoma, and adenoma. No invasion of the vasculature was identified on CT.

The dog had evidence of Cushing's disease, making adenocarcinoma more likely. The pituitary gland appeared normal on CT, ruling out pituitary dependent hyperadrenocoriticism. A laporoscopic resection of the left adrenal gland was performed. There was no vascular invasion at surgery. The histopathologic diagnosis was cortical carcinoma.

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