Stem and lead-in (multiple choice questions)

Last revised by Allison L Zwingenberger on 10 Apr 2025

The stem and lead-in are the first parts of [multiple choice questions](multiple-choice-questions) and are sometimes rolled into one short sentence or phrase. 

These have dual purposes: 

1. provide context for the question and provide any relevant information

2. instruct the examinee exactly what needs to be done to answer the question correctly

  • A 5-year-old Dachshund presents with acute paraparesis. [stem]

  • What is the most likely cause? [lead-in]

  • What is the term for heart failure caused by pericardial effusion?? [combined stem and lead-in] 

  • clear: the stem should be clearly written, and unambiguous; do not try and trick the examinee

  • short: try and keep the stem as short as possible without diminishing comprehension (e.g. avoid acronyms)

    avoid negatives

    • in most instances, stems should be worded to achieve a positive/true answer, as this reinforces knowledge

      • positive: "Which neoplasia is most likely to affect the skull in dogs?" 

      • negative: "Which neoplasia is least likely to affect the skull in dogs?"

  • sometimes the learning goal is a negative answer and if this is the case the negative term should be in ALL CAPS and emboldened (e.g. "Which of the following is FALSE?") to avoid misreading

  • read more about negative questions

  • avoid double negatives: double negatives are never needed and should be avoided

  • use the present tense

    • generally, the stem should be in the present tense  (e.g. "A 5-year-old neutered male pug presents with abdominal pain and a CT scan is performed")

  • avoid teaching: questions are questions, not didactic teaching. Therefore avoid including non-question specific facts within stems. 

When writing the stem, try to stick to a natural order that places content in an order that has maximal readability and limits confusion:

  1. age/sex/breed

  2. relevant history

  3. presenting signs and symptoms

  4. what was done

  5. lead-in question

The lead-in follows the stem and is used to instruct the examinee as to exactly what is required to answer the question correctly. It can either be in the form of a question or a phrase needing completion. 

  • question-type lead-in

    • "What is the most likely diagnosis?"

    • "Which of the following is FALSE?"

  • completion-type lead-in

    • "The tributary of the portal vein closest to the liver is..."

    • "All of the following are reasonable diagnoses EXCEPT..."

It is essential that for the completion type lead-in, that the alternatives (see below) are phrased in such a way that they grammatically finish the lead-in appropriately – in other words, you should be able to read the lead-in followed by each alternative, and it should make sense. 

Both the stem and lead-in should have normal sentence capitalization and punctuation. There are a few special notes specific to multiple choice questions:

  • question-type lead-ins should finish with a question mark ( ? ) 

    • e.g. "What diagnostic test would you recommend next?"

  • completion-type lead-ins should finish with an ellipsis ( ... )

    • e.g. "The differential diagnoses for a cranial mediastinal mass are... "

  • if the lead-in is asking to pick the single wrong answer negative question the negative word should be in ALL CAPS and emboldened, to make it harder to misread

    • e.g. "Which of the following is FALSE?"

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